• pex - PEX is a library and tool for generating .pex (Python EXecutable) files, which are self-contained, executable Python environments
• pyempaq - Python packager that creates a zipapp which setups the virtual environment, installs the dependencies and runs the application
• rye - a Hassle-Free Python Experience
• shiv - self-contained Python zipapps as outlined in PEP-441
• uv - An extremely fast Python package installer and resolver, written in Rust. Designed as a drop-in replacement for pip and pip-compile.